MRIreduce: ROI-Based Transformation of Neuroimages into High-Dimensional Data Frames

Converts NIfTI format T1/FL neuroimages into structured, high-dimensional 2D data frames with a focus on region of interest (ROI) based processing. The package incorporates the partition algorithm, which offers a flexible framework for agglomerative partitioning based on the Direct-Measure-Reduce approach. This method ensures that each reduced variable maintains a user-specified minimum level of information while remaining interpretable, as each maps uniquely to one variable in the reduced dataset. The partition framework is described in Millstein et al. (2020) <doi:10.1093/bioinformatics/btz661>. The package allows customization in variable selection, measurement of information loss, and data reduction methods for neuroimaging analysis and machine learning workflows.

Version: 1.0.0
Depends: R (≥ 3.5.0)
Imports: R6, Rcpp, fslr, neurobase, oro.nifti, parallel, partition, reshape2, reticulate
LinkingTo: Rcpp
Suggests: DT, EveTemplate, knitr, rmarkdown, testthat (≥ 3.0.0)
Published: 2026-04-21
DOI: 10.32614/CRAN.package.MRIreduce (may not be active yet)
Author: Joshua Milstein [aut], Jinyao Tian [aut, cre]
Maintainer: Jinyao Tian <jinyaoti at usc.edu>
License: MIT + file LICENSE
URL: https://uscbiostats.github.io/MRIreduce/
NeedsCompilation: yes
SystemRequirements: FSL (FMRIB Software Library, available at https://fsl.fmrib.ox.ac.uk/fsl/docs/#/install/index)
Additional_repositories: https://neuroconductor.org/releases/2020/05
Language: en-US
Materials: README
CRAN checks: MRIreduce results

Documentation:

Reference manual: MRIreduce.html , MRIreduce.pdf
Vignettes: Introduction to MRIreduce (source, R code)

Downloads:

Package source: MRIreduce_1.0.0.tar.gz
Windows binaries: r-devel: not available, r-release: MRIreduce_1.0.0.zip, r-oldrel: MRIreduce_1.0.0.zip
macOS binaries: r-release (arm64): MRIreduce_1.0.0.tgz, r-oldrel (arm64): not available, r-release (x86_64): MRIreduce_1.0.0.tgz, r-oldrel (x86_64): MRIreduce_1.0.0.tgz

Linking:

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